The Study Abstract: Santosa D, Suharti C, Riwant I, et al. Curcumin as adjuvant therapy to improve remission in myeloma patients: a pilot randomized clinical trial. Casp J Int Med. 2022;13:375–84. Background: The treatment for ineligible transplant multiple myeloma is melphalan prednisone. Curcumin has an anti-inflammatory and antiangiogenesis in cancer-directed to nuclear factor-kappa B (NF-kB) pathway. Interleukin 6 (IL-6), vascular …
Is Saffron Equal to a Prescription Drug for ADHD?
The Study Abstract: Baziar S, Aqamolaei A, Khadem E, et al. Crocus sativus L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study. J Child Adolesc Psychopharmacol. 2019;29(3):205-12. OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders of childhood and adolescence. About 30% of patients do not respond to stimulants or cannot tolerate their side effects. Thus, alternative medication, like …
Andrographis and Melatonin Promote Autophagy
The Study Abstract: Zhao Y, Wang C, Goel A. A combined treatment with melatonin and andrographis promotes autophagy and anti-cancer activity in colorectal cancer. Carcinogenesis. 2022 Jan 28:bgac008. doi: 10.1093/carcin/bgac008. Epub ahead of print. PMID: 35089340. Colorectal cancer (CRC) is one of the most frequent malignancies worldwide and remains one of the leading causes of cancer-related deaths in the United …
Red Ginseng Recharges After Post-Viral Fatigue
The Study Abstract: Teitelbaum J, Goudie S. An Open-Label, Pilot Trial of HRG80 Red Ginseng in Chronic Fatigue Syndrome, Fibromyalgia, and Post-Viral Fatigue. Pharmaceuticals. 2022; 15(1):43. Chronic fatigue syndrome and fibromyalgia (CFS/FMS) affect 2.1% of the world’s population and ~10–25% of people who have had COVID-19. Previous clinical data suggested that a unique Panax ginseng (C.A. Meyer, family Araliaceae) root extract (HRG80 Red …
Can Curcumin and Zinc Treat Prediabetes?
The Study Abstract: Karandish M, Mozaffari-Khosravi H, Mohammadi SM, Cheraghian B, Azhdari M. The effect of curcumin and zinc co-supplementation on glycemic parameters in overweight or obese prediabetic subjects: A phase 2 randomized, placebo-controlled trial with a multi-arm, parallel-group design. Phytother Res. 2021 Aug;35(8):4377-4387. Management of prediabetes is a critical step to prevent type-2 diabetes. Curcumin and zinc have been …
Is Propolis a Brain Booster?
The Study Abstract: Asama T, Hiraoka T, Ohkuma A, Okumura N, Yamaki A, Urakami K. Cognitive Improvement and Safety Assessment of a Dietary Supplement Containing Propolis Extract in Elderly Japanese: A Placebo-Controlled, Randomized, Parallel-Group, Double-Blind Human Clinical Study. Evid Based Complement Alternat Med. 2021 Feb 24;2021:6664217. Objectives. This study aimed to evaluate the effect of propolis on cognitive function in …
Curcumin May Curb Radiotherapy Side Effects
The Study Abstract: Arun P, Sagayaraj A, Azeem Mohiyuddin SM, Santosh D. Role of turmeric extract in minimizing mucositis in patients receiving radiotherapy for head and neck squamous cell cancer: a randomized, placebo-controlled trial. J Laryngol Otol. 2020 Feb 7:1-6. Objective: To determine the role of turmeric extract in reducing mucositis in patients undergoing radiotherapy for head and neck cancer. Methods: Sixty-one …
Ayurvedic Adaptogen Combo Boosts Brain Activity
The Study Abstract: Dimpfel W, Schombert L, Keplinger-Dimpfel IK, Panossian A. Pharmaceuticals (Basel). Effects of an Adaptogenic Extract on Electrical Activity of the Brain in Elderly Subjects with Mild Cognitive Impairment: A Randomized, Double-Blind, Placebo-Controlled, Two-Armed Cross-Over Study.2020 Mar 14;13(3):45. Background: The current and potential uses of adaptogens are mainly related to treatment of stress-induced fatigue, impaired cognitive function, mental illness, …
Anxiety Relief with a Specialized Echinacea Extract
The Study Abstract: Double-blind, placebo controlled trial of the anxiolytic effects of a standardized Echinacea extract. Earlier studies suggested that a specific Echinacea preparation might decrease anxiety. To further study the issue, we performed a double blind, placebo controlled trial with a standardized Echinacea angustifolia root extract. Participants were volunteers scoring above 45 points on the state or on the …
Andrographis Inhibits Colon Cancer Cells
The Study Abstract: Sharma P, Shimura T, Banwait JK, Goel A. Andrographis-mediated chemosensitization through activation of ferroptosis and suppression of β-catenin/Wnt-signaling pathways in colorectal cancer. Carcinogenesis. 2020 Aug 24:bgaa090. Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality in the USA. As much as 50–60% of CRC patients develop resistance to 5-fluorouracil (5FU)-based chemotherapeutic regimens, attributing the …